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Urinary incontinence was highly prevalent at diagnosis in women with early-stage breast cancer, a prospective, observational study has found. In addition, there is some evidence supporting an increased prevalence of urinary incontinence in women with breast cancer who were treated with endocrine therapy and those at high-risk of the disease who received endocrine therapy as chemoprevention. Nevertheless, many of the studies investigating the impact of systemic therapy for breast cancer on bladder symptoms were population-based studies in which preexisting urinary incontinence arising from causes other than breast cancer therapy was not evaluated.
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