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Examining what factors mediate treatment effect in chronic low back pain

from European Journal of Pain

Examining what factors mediate treatment effect in chronic low back pain European Journal of Pain Cognitive Functional Therapy (CFT) is a physiotherapist‐led individualised intervention for people with people with non‐specific chronic low back pain (CLBP), involving biopsychosocial pain education, graded movement exposure and lifestyle coaching. A multicenter randomized controlled trial (RCT), including 206 participants with CLBP in Ireland, supported CFT's effectiveness for reducing disability, but not pain, compared to a group exercise and education intervention. In this study, causal mediation analysis was used to determine whether the effect of CFT on disability and the lack of effect on pain (relative to a group exercise and education intervention) is mediated by certain psychological and lifestyle factors. READ MORE

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