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Immediate dialysis no better than wait-until-necessary approach, researchers find
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University of Alberta Faculty of Medicine & Dentistry via EurekAlert
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In the largest international study of its kind, researchers at the University of Alberta and Toronto's St. Michael's Hospital found that an accelerated renal-replacement therapy strategy did not reduce mortality after three months, compared to a standard strategy for critically ill patients with acute kidney injury. The Standard vs. Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial was co-led by Sean Bagshaw, professor and chair of the University of Alberta's Department of Critical Care Medicine, and Ron Wald, nephrologist and medical director of hemodialysis at St. Michael's and associate professor of medicine at the University of Toronto. "This is the largest trial to tackle a question that has been vexing clinicians for more than 30 years," said Bagshaw. "The critical care and nephrology communities have been eagerly awaiting further information to guide the question, 'When is the ideal time to start dialysis therapy in critically ill patients admitted to Intensive Care Unit (ICU) with acute kidney injury?'"
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