From Name

From Email

To Name

To Email

Message

Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants

from Nature Communication

Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants Nature Communication Current doctrine is that microvascular inflammation (MVI) triggered by a transplant -recipient antibody response against alloantigens (antibody-mediated rejection) is the main cause of graft failure. Here, we show that histological lesions are not mediated by antibodies in approximately half the participants in a cohort of 129 renal recipients with MVI on graft biopsy. READ MORE

more