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Liver transplantation (LT) is curative for most patients with hepatocellular carcinoma (HCC). However, 10â€15% of patients experience HCC recurrence. Patients who are reported as within Milan criteria by imaging are frequently found to be outside the criteria on explant. This understaging of HCC worsens postâ€LT outcomes. However, risk factors for understaging have not been elucidated. Furthermore, it is not known if there is regional or centerâ€level variation in understaging. Researchers conducted a retrospective analysis of adult patients transplanted for HCC in the United Network for Organ Sharing (UNOS) database between 2012 and 2016.
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