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The enemy within: Safeguarding against the spread of intracellular bacteria

from Walter and Eliza Hall Institute via EurekAlert!

The enemy within: Safeguarding against the spread of intracellular bacteria Walter and Eliza Hall Institute via EurekAlert! Melbourne researchers have revealed the multiple, intertwined cell death systems that prevent the spread of the "intracellular" bacterium Salmonella, an important cause of typhoid fever which kills more than 100,000 people annually. The team revealed that the spread of Salmonella is curtailed by the death of infected cells, but, surprisingly, cells can die in several distinct ways. Although Salmonella continuously seeks to outsmart infected cells by blocking their suicide, cells have evolved impressive "back-up" strategies to ensure that the infected cell can still die and thus protect the body from Salmonella infection and consequent typhoid fever. READ MORE

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