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'Immune Profiles' Shed Light on COVID-19 Disease Course

from MedPage Today

'Immune Profiles' Shed Light on COVID-19 Disease Course MedPage Today Several "immune profiles" emerged among COVID-19 patients, which appeared to lead to different disease trajectories, researchers found. In a study of 113 patients, three distinct severity clusters emerged, as patients with moderate disease were characterized by "low expression of proinflammatory cytokines and enrichment in tissue repair genes"; those with "highly elevated proinflammatory cytokines," on the other hand, "developed worse disease and many died," researchers reported. READ MORE

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