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Progestins are commonly prescribed firstâ€line drugs for endometriosis. High rates of nonâ€response and intolerance to these drugs have been previously reported. However, no study to date has investigated the characteristics and comorbidities of the patients taking progestins in relation to treatment outcomes, thus identifying which patients will respond or tolerate the treatment is currently impossible. The purpose of this study, therefore, was to identify risk factors for nonâ€response and discontinuation of Dienogest (DNG) in patients with endometriosis.
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