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Pathogen-Induced Tissue-Resident Memory TH17 (TRM17) Cells Amplify Autoimmune Kidney Disease

from Science Immunology

Pathogen-Induced Tissue-Resident Memory TH17 (TRM17) Cells Amplify Autoimmune Kidney Disease Science Immunology Although it is well established that microbial infections predispose to autoimmune diseases, the underlying mechanisms remain poorly understood. After infection, tissue-resident memory T (TRM) cells persist in peripheral organs and provide immune protection against reinfection. However, whether TRM cells participate in responses unrelated to the primary infection, such as autoimmune inflammation, is unknown. READ MORE

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