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Human Articular Cartilage is Orthotropic where Microstructure, Micromechanics, and Chemistry Vary with Depth, Split-line Orientation

from Osteoarthritis and Cartilage

Human Articular Cartilage is Orthotropic where Microstructure, Micromechanics, and Chemistry Vary with Depth, Split-line Orientation Osteoarthritis and Cartilage Quantitative, micrometer length scale assessment of human articular cartilage is essential to enable progress toward new functional tissue engineering approaches, including utilization of emerging 3-D bioprinting technologies, and for improved computational modeling of the osteochondral unit. Thus the objective of this study was to characterize the structural organization, material properties, and chemical composition of human skeletally mature articular cartilage with respect to depth and defined morphological features: normal to the articulating surface, parallel to the split-line, and transverse to the split-line. READ MORE

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