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The bioavailability and maturing clearance of doxapram in preterm infants

from <I>Pediatric Research </i>– Authors include SPR Members Peter Andriessen, Kian D. Liem

The bioavailability and maturing clearance of doxapram in preterm infants Pediatric Research – Authors include SPR Members Peter Andriessen, Kian D. Liem A common symptom of neurological and respiratory underdevelopment in preterm born infants is apnea of prematurity (AOP). AOP decreases oxygen saturation and can result in hypoxic episodes that are harmful to the infant’s short- and long-term neurodevelopmental outcomes.1 Endotracheal intubation is a potentially dangerous procedure in patients as small as preterm babies, and invasive ventilation is related to chronic lung disease. READ MORE

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