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Identification of homozygous somatic <i>DICER1</i> mutation in pleuropulmonary blastoma

from Journal of Pediatric Hematology/Oncology

Identification of homozygous somatic DICER1 mutation in pleuropulmonary blastoma Journal of Pediatric Hematology/Oncology Pleuropulmonary blastoma (PPB) is a rare, progressive, and aggressive malignant intrathoracic tumor observed during childhood. Mutations in the DICER1 gene have been considered a major etiologic factor of PPB and cause a variety of tumor types in children and young adults. Researchers presented a 3-year-old boy with type II PPB. READ MORE

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