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Treating cytomegalovirus-induced hemophagocytic lymphohistiocytosis in a child with leukemia

from Journal of Pediatric Hematology/Oncology

Treating cytomegalovirus-induced hemophagocytic lymphohistiocytosis in a child with leukemia Journal of Pediatric Hematology/Oncology Hemophagocytic lymphohistiocytosis (HLH) is a syndrome characterized by a hyperinflammatory state due to an aberrant activation of the immune cells. It can be familial or secondary to malignancy, autoimmune or metabolic diseases. Most HLH cases are triggered by infection. Histiocyte society suggested HLH-2004 protocol for diagnosis and treatment of both forms. Here, researchers presented a 3-year-old girl with B-cell acute lymphoblastic leukemia who developed HLH secondary to cytomegalovirus infection during maintenance therapy. READ MORE

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