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Osteopontin (OPN) has been investigated as a biomarker for cancer and nonmalignant diseases during the last decades. Data about OPN as a potential biomarker in childhood diseases are still sparse, and reference values are not available in children. Researchers aimed to establish reference values for children from birth to young adulthood and evaluate whether there are ageâ€, genderâ€, and weightâ€specific differences.
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