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Pembrolizumab (Keytruda) in combination with several chemotherapy partners led to a statistically significant and clinically meaningful improvement in progression-free survival (PFS) compared with chemotherapy alone as a first-line treatment for patients with locally recurrent, inoperable, or metastatic triple-negative breast cancer (TNBC) whose tumors expressed PD-L1, according to results of the phase 3 KEYNOTE-355 trial that were presented during the 2020 ASCO Virtual Scientific Program.
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