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Oxygenation improved in hospitalized patients with COVID-19 with severe hypoxemic respiratory failure when they were placed in the prone position, a small study in New York City found. One hour after initiation, oxyhemoglobin saturation increased by a median 7 percentage points from baseline in awake, spontaneously breathing patients with at least one awake session of the prone position, reported Sanja Jelic, MD, of Columbia University Vagelos College of Physicians and Surgeons in New York City, and colleagues. Among 25 patients proned for at least one hour, 19 achieved oxyhemoglobin saturation of 95% or greater, though seven of these were eventually intubated anyway, the investigators wrote in a research letter in JAMA Internal Medicine.
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