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HSCT with total body irradiation vs. chemotherapy-based conditioning improves ALL outcomes

from HemOnc Today via Healio

HSCT with total body irradiation vs. chemotherapy-based conditioning improves ALL outcomes HemOnc Today via Healio Allogeneic hematopoietic stem cell transplants with total body irradiation and etoposide versus chemotherapy-based conditioning regimens conferred superior OS for children with acute lymphoblastic leukemia, randomized study results showed. The results, presented during the virtual European Hematology Association Annual Congress, also demonstrated that bulsufan- or treosulfan-based chemotherapy conditioning regimens that included fludarabine and thiotepa are valuable alternative options for patients ineligible for total body irradiation because of comorbidities or age. READ MORE

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