From Name

From Email

To Name

To Email

Message

Intensive renal replacement therapy may increase risk for MV extubation failure

from Pulmonology Advisor

Intensive renal replacement therapy may increase risk for MV extubation failure Pulmonology Advisor In critically ill mechanically ventilated patients with acute kidney injury (AKI), more intensive renal replacement therapy (RRT) may lead to a greater risk of failure to extubate, according to a study published in CHEST. Severe AKI may require support through intermittent or continuous RRT while the kidneys recover function. However, increasing the RRT dose is associated with electrolyte abnormalities such as hypophosphatemia and hypokalemia, enhanced elimination of antibiotics leading to inadequate dosing, excessive nutrient losses such as amino acids and proteins, and lower urine output. READ MORE

more