Very low birthweight preterm infants fed
mothers' own milk need nutritional supplementation, traditionally achieved with cow's milk derived fortifier CMDF
and preterm formula if MOM is insufficient. CM products
have been associated with diverse major morbidities. The current
recommendation is to preferentially replace PTF with donor milk
to produce a 100 percent human milk base diet, usually fortified with CMDF. The objective of this study was to identify whether CMDF, even when
fed with a 100 percent HM base diet, is related to an increased risk of
major morbidities.
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