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Researchers Discover How Enzyme Protects Cells from DNA Damage

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Researchers Discover How Enzyme Protects Cells from DNA Damage Lab Manager A research team from Mount Sinai has unraveled for the first time the three-dimensional structure and mechanism of a complex enzyme that protects cells from constant DNA damage, opening the door to discovery of new therapeutics for the treatment of chemotherapy-resistant cancers. In a study published in Nature Structural & Molecular Biology in August, the researchers described how they used advanced cryo-electron microscopy to gain detailed insights into the enzyme known as DNA polymerase ζ. READ MORE

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